Below is an excerpt from the Science story by Chris Tachibana:
The list of specific areas within systems biology is almost comically long, and includes everything from cutting-edge computer science to traditional life sciences. Fortunately, in this field, collaboration is the name of the game. Galetti Professor of Bioengineering at the University of California, San Diego (UCSD) Bernhard Palsson says systems biology includes "an understanding of networks, biological systems and linear algebra, genomics and genetics, the biochemistry of gene products, and how everything fits into the three-dimensional architecture of the cell." Hlatky says that attacking the complex, nonlinear nature of biology requires "a team of individuals collectively versed in the traditional biological as well as the quantitative sciences, from cell and molecular biology to physics, chemistry, computer science, and mathematics."
Palsson leads the Systems Biology Research Group within the Department of Bioengineering in the UC San Diego Jacobs School of Engineernig.