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Snapshots from the UC San Diego Jacobs School of Engineering.
Shu Chien, Doctor of Science: As a doctor, researcher and professor, Chien has made seminal contributions to fields of biology, medicine and engineering. His primary areas of research are cardiovascular physiology, molecular and cellular bioengineering, and stem cell regulation. He is the author of more than 500 peer-reviewed scientific articles and editor of 11 books. He has been a leader of numerous professional societies and the recipient of countless awards, including the National Medal of Science, which he received from President Obama in 2011.

For example, Zhang’s lab has shown that nanoparticles stuffed with a cocktail of cancer-fighting drugs can be hidden from the body’s immune system by simply wrapping them in the membrane of a red blood cell. His red blood cell membrane cloaked nanoparticles were featured in a front-page story by UT San Diego last November and in the Proceedings of the National Academy of Sciences.
Nanoparticles are less than 100 nanometers in size, about the same size as a virus. “This is the first work that combines the natural cell membrane with a synthetic nanoparticle for drug delivery applications.” said Zhang, who is also affiliated with Moores UCSD Cancer Center.
Zhang is also working on biologically responsive nanostructures that offer a new way to deliver antimicrobial agents directly to the site of bacterial infections such as methicillin-resistant Staphylococcus aureus. Zhang’s team use phospholipid liposomes to deliver the antibiotics. But liposomes by themselves wouldn’t last long enough to deliver an effective treatment so Zhang has stabilized them with chitosan-coated gold nanoparticles.
You can learn more about the Zhang Research Group’s gold nanoparticle-stabilized liposomes for bacterial skin infections at the April 12 Research Expo 2012 when Soracha Thamphiwatana, a nanoengineering graduate student in Zhang’s lab, will present a poster on this research, which was published last year in Chemical & Engineering News.
The Unilever Award is one of the most competitive and prestigious national awards offered by the ACS Division of Colloid and Surface Chemistry. Zhang will receive the award this summer during the 86th ACS Colloids and Surface Science Symposium in Baltimore June 12.
Four engineering faculty members with technology transfer success stories discussed the challenges of the commercialization process during a March 14 dinner celebrating the 10th anniversary of the von Liebig Center for Entrepreneurism and Technology Advancement. The von Liebig Center offers seed funding and advisory services and is part of the Jacobs School of Engineering at the University of California, San Diego.
“If we do research and just put it on the shelf to collect dust, we’re not doing our job,” said Frieder Seible, dean of the Jacobs School of Engineering. “We need to transfer our discoveries from the research lab to society.” During the dinner, which was hosted by the UC San Diego Chancellor’s Associates, Seible said the von Liebig Center had transformed the culture of the engineering school, giving students and faculty an entrepreneurial mindset. The Chancellor’s Associates are generous group of alumni, parents and friends who give $2,500 or more each year to be used at the Chancellor's discretion to fund the university's greatest needs.
Stephen Flaim, who is deputy director of the center and one of its several technology and business advisors, talked about the so-called Valley of Death, a gap between the laboratory and the marketplace that can fell even the most promising technology. Lacking funding and a connection with private sector investors and collaborators, researchers can easily get stuck. “There is a gap before the gap,” said Flaim. “That gap is the step from the university out to the private sector. What we did here at the von Liebig Center was figure out a mechanism and an infrastructure that allowed us to make the technologies inside a university recognizable at an earlier stage.”
Read our story about the success stories of UC San Diego Jacobs School of Engineering professors David Kriegman, computer science and engineering; Rene Cruz, electrical and computer engineering; Sujit Dey, electrical and computer engineering; and Geert Schmid-Schönbein, bioengineering. You can learn more about the cutting edge student research happening in faculty labs, including those of Schmid-Schönbein, Dey and Cruz at Research Expo April 12. Here's a snapshot of what their students will be presenting during the poster session: QUERY-BASED MODELS AND ALGORITHMS FOR DISTRIBUTED INFORMATION DISSEMINATION
Student(s): Efecan Poyraz
Professor(s): Rene L. Cruz
ADAPTATION OF VIDEO ENCODING TO ADDRESS DYNAMIC THERMAL MANAGEMENT EFFECTS
Student(s): Seyed Ali Mirtar
Professor(s): Sujit Dey
DYNAMIC BASE STATION RECONFIGURATION FOR BATTERY EFFICIENT VIDEO DOWNLOAD
Student(s): Ranjini B Guruprasad
Professor(s): Sujit Dey
MODELING, CHARACTERIZING, AND ENHANCING USER EXPERIENCE IN CLOUD MOBILE RENDERING
Student(s): Yao Liu
Professor(s): Sujit Dey
USER INTEREST ESTIMATION BASED ON VIDEO WEBPAGE CLASSIFICATION
Student(s): Chetan Kumar Verma
Professor(s): Sujit Dey
VIDEO CACHING IN THE WIRELESS CLOUD: ALGORITHMS AND IMPACT ON DELAY AND CAPACITY
Student(s): Hasti Ahlehagh
Professor(s): Sujit Dey